Every year, global health experts are faced with a high-stakes decision: Which influenza strains should go into the next seasonal vaccine? The choice must be made months in advance, long before flu season even begins, and it can often feel like a race against the clock. If the selected strains match those that circulate, the…
Environmental scientists are increasingly using enormous artificial intelligence models to make predictions about changes in weather and climate, but a new study by MIT researchers shows that bigger models are not always better. The team demonstrates that, in certain climate scenarios, much simpler, physics-based models can generate more accurate predictions than state-of-the-art deep-learning models. Their…
Back in the 17th century, German astronomer Johannes Kepler figured out the laws of motion that made it possible to accurately predict where our solar system’s planets would appear in the sky as they orbit the sun. But it wasn’t until decades later, when Isaac Newton formulated the universal laws of gravitation, that the underlying…
Cognitive readiness denotes a person’s ability to respond and adapt to the changes around them. This includes functions like keeping balance after tripping, or making the right decision in a challenging situation based on knowledge and past experiences. For military service members, cognitive readiness is crucial for their health and safety, as well as mission…
Using machine learning, MIT chemical engineers have created a computational model that can predict how well any given molecule will dissolve in an organic solvent — a key step in the synthesis of nearly any pharmaceutical. This type of prediction could make it much easier to develop new ways to produce drugs and other useful…
Within the past few years, models that can predict the structure or function of proteins have been widely used for a variety of biological applications, such as identifying drug targets and designing new therapeutic antibodies. These models, which are based on large language models (LLMs), can make very accurate predictions of a protein’s suitability for…
Using artificial intelligence, MIT researchers have come up with a new way to design nanoparticles that can more efficiently deliver RNA vaccines and other types of RNA therapies. After training a machine-learning model to analyze thousands of existing delivery particles, the researchers used it to predict new materials that would work even better. The model…
With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA). Using generative AI algorithms, the research team designed more than 36 million possible compounds and computationally screened them for antimicrobial properties. The top candidates they discovered are structurally distinct from any…
“Manufacturing is the engine of society, and it is the backbone of robust, resilient economies,” says John Hart, head of MIT’s Department of Mechanical Engineering (MechE) and faculty co-director of the MIT Initiative for New Manufacturing (INM). “With manufacturing a lively topic in today’s news, there’s a renewed appreciation and understanding of the importance of…
Is this movie review a rave or a pan? Is this news story about business or technology? Is this online chatbot conversation veering off into giving financial advice? Is this online medical information site giving out misinformation? These kinds of automated conversations, whether they involve seeking a movie or restaurant review or getting information about…